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Early Life Origins of Pediatric and Adult Diseases

  • Cincinnati Children's, Sabin Auditorium 3333 Burnet Avenue Cincinnati, OH, 45229 United States (map)

Xiaobin Wang, MD, MPH, ScD

Zanvyl Krieger Professor
Director, Center on the Early Life Origins of Disease
Department of Population, Family and Reproductive Health
Johns Hopkins University Bloomberg School of Public Health
Professor of Pediatrics
Johns Hopkins University School of Medicine


Early Life Origins of Pediatric and Adult Diseases: Envisioning a new paradigm to optimize health across the lifespan and generation

This presentation was part of Cincinnati Children’s Pediatric Grand Rounds.

Objectives

By the end of this presentation, attendees will be able to:

  1. Know the paradigm of developmental origins of health and diseases (DOHaD).

  2. Become familiar with relevant research regarding what and how early life factors could influence future disease risk, highlighting the complex interplay of genetic, epigenetic, and environmental factors during critical developmental windows.

  3. Stimulate discussions on challenges and opportunities to advance DOHaD research to inform ways that maternal and child health care and services are organized and delivered to optimize health across the lifespan and generation.


About the Speaker

Dr. Wang is Zanvyl Krieger Professor in Child Health, Director of the Center on the Early Life Origins of Disease at Johns Hopkins University Bloomberg School of Public Health, and Professor of Pediatrics and a board-certified pediatrician at Johns Hopkins School of Medicine.

Dr. Wang has devoted her entire career to improve maternal and child health across the life course. Her research unit biomarkers, clinical medicine, and epidemiology. She established the Boston Birth Cohort (BBC), consisting of predominantly US urban, low income, underrepresented minority mothers and children (N~8,700 dyads, ~60% Black, ~25% Latinx), funded continuously by the NIH for 20+ years. Dr. Wang has served as the PI of a dozen NIH funded large-scale molecular epidemiological studies and led multi-institution teams to investigate environmental, nutritional, genomic, epigenomic, proteomic, and metabolomic factors during critical developmental windows aiming to identify early life origins of major pediatric and adult chronic diseases to inform early risk assessment and primary prevention. Dr. Wang has published over 380 peer-reviewed articles; many appear in high impact medical and public health journals. She is an elected member of the National Academy of Medicine.


Accreditation

In support of improving patient care, Cincinnati Children’s Hospital Medical Center is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing (ANCC), to provide continuing education for the healthcare team.

Cincinnati Children’s designates the live activity for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.